Harkiss KJ; Swift D 1970

• Authors: Harkiss KJ; Swift D
• Title: 4 methyl-2 6 naphthyridine a new plant constituent from Antirrhinum majus
• Location: Tetrahedron Letters, 55. 1970 4773-4774
• Abstract: The synthesisof 2,6-naphthyridine has been described, but its methyl derivates have not yet been prepared. The natural occurrence of simple naphthyridines has hitherto been unrecorded. We with therefore, to report the isolation from Antirrhinum majus of a base which we believe to be 4-methyl-2,6-naphthyridine. Other bases were also obtained, but in quantities insufficient for characterisation. Thin-layer chromatography of alcoholic extracts from the dried aerial parts of A. majus showed the presence of five compounds which react with Dragenhoff's reagent.